3B8R: Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor

PDB ID: 3B8RDownload
MMDB ID: 63485
PDB Deposition Date: 2007/11/1
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3B8R: monomeric; determined by author and by software (PISA)
Molecular Components in 3B8R
Label Count Molecule
Protein (1 molecule)
1
Vascular Endothelial Growth Factor Receptor 2
(Gene symbol: KDR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamideN-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303