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3EFW:
Structure of AuroraA with pyridyl-pyrimidine urea inhibitor
PDB ID:
3EFW
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MMDB ID:
98291
PDB Deposition Date:
2008/9/10
Updated in MMDB:
2013/06
Experimental Method:
x-ray diffraction
Resolution:
2.29 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 3EFW: monomeric; determined by author and by software (PISA)
Molecular Components in 3EFW
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase 6
(Gene symbol:
AURKA
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
2
1
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303