2ZMI: Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and/or Partial Agonism

PDB ID: 2ZMIDownload
MMDB ID: 66430
PDB Deposition Date: 2008/4/19
Updated in MMDB: 2008/09
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2ZMI: dimeric; determined by author and by software (PISA)
Molecular Components in 2ZMI
Label Count Molecule
Proteins (2 molecules)
1
Vitamin D3 Receptor
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 1
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]pent-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol(1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]pent-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303