2VWO: Aminopyrrolidine Factor Xa inhibitor

PDB ID: 2VWODownload
MMDB ID: 239984
PDB Deposition Date: 2008/6/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2VWO: monomeric; determined by author
Molecular Components in 2VWO
Label Count Molecule
Protein (1 molecule)
1
Activated Factor XA Heavy Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE
2
1
CALCIUM IONCALCIUM ION
3
2
SODIUM IONSODIUM ION
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303