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3FPD:
G9a-like protein lysine methyltransferase inhibition by BIX-01294
PDB ID:
3FPD
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MMDB ID:
69732
PDB Deposition Date:
2009/1/5
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.4 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3FPD: dimeric; determined by author and by software (PISA)
Molecular Components in 3FPD
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 5
(Gene symbol:
EHMT1
)
Chemicals and Non-standard biopolymers (12 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINE
2
2
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
3
8
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303