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3L13:
Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors
PDB ID:
3L13
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MMDB ID:
80174
PDB Deposition Date:
2009/12/10
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3L13: monomeric; determined by author and by software (PISA)
Molecular Components in 3L13
Label
Count
Molecule
Protein (1 molecule)
A
1
Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol:
PIK3CG
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
[3-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]methanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303