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3LPB:
Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor
PDB ID:
3LPB
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MMDB ID:
81732
PDB Deposition Date:
2010/2/5
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3LPB: monomeric; determined by author and by software (PISA)
Molecular Components in 3LPB
Label
Count
Molecule
Protein (1 molecule)
A
1
Tyrosine-protein Kinase Jak2
(Gene symbol:
JAK2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303