3E8D: Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

PDB ID: 3E8DDownload
MMDB ID: 67349
PDB Deposition Date: 2008/8/19
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3E8D: dimeric; determined by author and by software (PISA)
Molecular Components in 3E8D
Label Count Molecule
Proteins (2 molecules)
1
Rac-beta Serine/threonine-protein Kinase
Molecule annotation
1
Glycogen Synthase Kinase-3 Beta Peptide
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303