4JQ7: Crystal structure of EGFR kinase domain in complex with compound 2a

PDB ID: 4JQ7Download
MMDB ID: 111097
PDB Deposition Date: 2013/3/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.73  Å
Source Organism:
Similar Structures:
Biological Unit for 4JQ7: dimeric; determined by author and by software (PISA)
Molecular Components in 4JQ7
Label Count Molecule
Proteins (2 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol(2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303