2XBV: Factor Xa In Complex With A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor

PDB ID: 2XBVDownload
MMDB ID: 83778
PDB Deposition Date: 2010/4/15
Updated in MMDB: 2010/08
Experimental Method:
x-ray diffraction
Resolution: 1.66  Å
Source Organism:
Similar Structures:
Biological Unit for 2XBV: dimeric; determined by author and by software (PISA)
Molecular Components in 2XBV
Label Count Molecule
Proteins (2 molecules)
1
Activated Factor XA Heavy Chain
(Gene symbol: F10)
Molecule annotation
1
Factor X Light Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(3r,4r)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic Acid 3-[(5-chloro-pyridin-2-yl)-amide]-4-{[2-fluoro-4-(2-oxo-2h-pyridin-1-yl)-phenyl]-amide}(3r,4r)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic Acid 3-[(5-chloro-pyridin-2-yl)-amide]-4-{[2-fluoro-4-(2-oxo-2h-pyridin-1-yl)-phenyl]-amide}
2
1
Calcium IonCalcium Ion
3
1
Sodium IonSodium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303