3OXI: Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of JNK for the Treatment of Neurodegenerative Diseases

PDB ID: 3OXIDownload
MMDB ID: 90299
PDB Deposition Date: 2010/9/21
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3OXI: dimeric; determined by author and by software (PISA)
Molecular Components in 3OXI
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 10
(Gene symbol: MAPK10)
Molecule annotation
1
Mitogen-activated Protein Kinase 8 Interacting Protein 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
methyl 3-[(thiophen-2-ylacetyl)amino]thiophene-2-carboxylatemethyl 3-[(thiophen-2-ylacetyl)amino]thiophene-2-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303