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2X6E:
Aurora-A bound to an inhibitor
PDB ID:
2X6E
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MMDB ID:
83152
PDB Deposition Date:
2010/2/17
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
3.35 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2X6E: monomeric; determined by author and by software (PISA)
Molecular Components in 2X6E
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase 6
(Gene symbol:
AURKA
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-BROMO-7-{4-[(5-METHYLISOXAZOL-3-YL)METHYL]PIPERAZIN-1-YL}-2-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-IMIDAZO[4,5-B]PYRIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303