2XM9: Structure of a small molecule inhibitor with the kinase domain of Chk2

PDB ID: 2XM9Download
MMDB ID: 87776
PDB Deposition Date: 2010/7/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2XM9: dimeric; determined by author and by software (PISA)
Molecular Components in 2XM9
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase Chk2
(Gene symbol: CHEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol
2
2
NITRATE IONNITRATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303