3Q2H: Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4

PDB ID: 3Q2HDownload
MMDB ID: 89553
PDB Deposition Date: 2010/12/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 3Q2H: monomeric; determined by author and by software (PISA)
Molecular Components in 3Q2H
Label Count Molecule
Protein (1 molecule)
1
a Disintegrin and Metalloproteinase With Thrombospondin Motifs 1
(Gene symbol: ADAMTS1)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
ZINC IONZINC ION
2
3
CADMIUM IONCADMIUM ION
3
10
NICKEL (II) IONNICKEL (II) ION
4
2
MAGNESIUM IONMAGNESIUM ION
5
2
SODIUM IONSODIUM ION
6
1
N-[(2S,4S)-1-({4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]piperidin-1-yl}sulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamideN-[(2S,4S)-1-({4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]piperidin-1-yl}sulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303