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2Y7X:
The Discovery Of Potent And Long-acting Oral Factor Xa Inhibitors With Tetrahydroisoquinoline And Benzazepine P4 Motifs
PDB ID:
2Y7X
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MMDB ID:
89156
PDB Deposition Date:
2011/2/2
Updated in MMDB:
2017/06
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2Y7X: dimeric; determined by author and by software (PISA)
Molecular Components in 2Y7X
Label
Count
Molecule
Proteins (2 molecules)
A
1
Activated Factor XA Heavy Chain
(Gene symbol:
F10
)
B
1
Factor X Light Chain
(Gene symbol:
F10
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
6-Chloro-N-[(3s)-1-(5-Fluoro-1,2,3,4-Tetrahydroisoquinolin-6-Yl)-2-Oxo-Pyrrolidin-3-Yl]naphthalene-2-Sulfonamide
2
1
Calcium Ion
3
1
Magnesium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303