2XNO: Structure of Nek2 bound to CCT243779

PDB ID: 2XNODownload
MMDB ID: 89473
PDB Deposition Date: 2010/8/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 2XNO: monomeric; determined by software (PISA)
Molecular Components in 2XNO
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Nek2
(Gene symbol: NEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
5-{6-[(1-methylpiperidin-4-yl)oxy]-1H-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide5-{6-[(1-methylpiperidin-4-yl)oxy]-1H-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide
2
2
CHLORIDE IONCHLORIDE ION
3
11
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
GLYCEROLGLYCEROL
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303