NCBI
National Center for
Biotechnology Information
Search
3LGP:
Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor
PDB ID:
3LGP
Download
MMDB ID:
83622
PDB Deposition Date:
2010/1/21
Updated in MMDB:
2021/10
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3LGP: monomeric; determined by author and by software (PISA)
Molecular Components in 3LGP
Label
Count
Molecule
Protein (1 molecule)
A
1
Disintegrin and Metalloproteinase Domain-containing Protein 17
(Gene symbol:
ADAM17
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC ION
2
1
(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-{[2-(trifluoromethyl)-1H-benzimidazol-1-yl]methyl}thiophen-2-yl)methyl]butanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303