3NU0: Design, Synthesis, Biological Evaluation and X-ray Crystal Structure of Novel Classical 6,5,6-TricyclicBenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors

PDB ID: 3NU0Download
MMDB ID: 90789
PDB Deposition Date: 2010/7/6
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.35  Å
Source Organism:
Similar Structures:
Biological Unit for 3NU0: monomeric; determined by author and by software (PISA)
Molecular Components in 3NU0
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reducatase
(Gene symbol: DHFR)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
3
* Click molecule labels to explore molecular sequence information.

Citing MMDB