3SFC: Structure-based Optimization Of Potent 4- And 6-azaindole-3- Carboxamides As Renin Inhibitors

PDB ID: 3SFCDownload
MMDB ID: 93334
PDB Deposition Date: 2011/6/13
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3SFC: monomeric; determined by author
Molecular Components in 3SFC
Label Count Molecule
Protein (1 molecule)
1
Renin
(Gene symbol: REN)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
3
GlycerolGlycerol
3
2
[7-Benzyl-2-(5-Fluoro-2-Methylphenoxy)-1-Phenyl-1h-Pyrrolo[2,3-C]pyridin-3-Yl](Piperazin-1-Yl)methanone[7-Benzyl-2-(5-Fluoro-2-Methylphenoxy)-1-Phenyl-1h-Pyrrolo[2,3-C]pyridin-3-Yl](Piperazin-1-Yl)methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303