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3S2A:
Crystal structure of PI3K-gamma in complex with a quinoline inhibitor
PDB ID:
3S2A
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MMDB ID:
91273
PDB Deposition Date:
2011/5/16
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3S2A: monomeric; determined by author and by software (PISA)
Molecular Components in 3S2A
Label
Count
Molecule
Protein (1 molecule)
A
1
Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol:
PIK3CG
)
Chemicals and Non-standard biopolymers (4 molecules)
1
3
SULFATE ION
2
1
N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303