2YEK: Crystal Structure Of The First Bromodomain Of Human Brd2 With The Inhibitor Gsk525762 (Ibet)

PDB ID: 2YEKDownload
MMDB ID: 91737
PDB Deposition Date: 2011/3/25
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 2YEK: dimeric; determined by author and by software (PISA)
Molecular Components in 2YEK
Label Count Molecule
Proteins (2 molecules)
2
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303