2ZDT: Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor

PDB ID: 2ZDTDownload
MMDB ID: 66867
PDB Deposition Date: 2007/11/27
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZDT: monomeric; determined by author and by software (PISA)
Molecular Components in 2ZDT
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 10
(Gene symbol: MAPK10)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1H)-yl)methyl]benzoic acid4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1H)-yl)methyl]benzoic acid
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303