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3VF9:
Crystal Structure of Spleen Tyrosine Kinase Syk Catalytic Domain with Thienopyrazolylindole Inhibitor 027
PDB ID:
3VF9
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MMDB ID:
99201
PDB Deposition Date:
2012/1/9
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 3VF9: monomeric; determined by author and by software (PISA)
Molecular Components in 3VF9
Label
Count
Molecule
Protein (1 molecule)
A
1
Tyrosine-protein Kinase SYK
(Gene symbol:
SYK
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-{2-[5-(difluoromethyl)-2H-thieno[3,2-c]pyrazol-3-yl]-1H-indol-6-yl}pentan-3-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303