4LFV: Crystal structure of human FPPS in complex with YS0470 and two molecules of inorganic phosphate

PDB ID: 4LFVDownload
MMDB ID: 118241
PDB Deposition Date: 2013/6/27
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4LFV: dimeric; determined by author and by software (PISA)
Molecular Components in 4LFV
Label Count Molecule
Proteins (2 molecules)
2
Farnesyl Pyrophosphate Synthase
(Gene symbol: FDPS)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
[({4-[4-(propan-2-yloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)[({4-[4-(propan-2-yloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)
2
4
PHOSPHATE IONPHOSPHATE ION
3
6
MAGNESIUM IONMAGNESIUM ION
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303