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4DPF:
Bace-1 In Complex With A Hea-Macrocyclic Type Inhibitor
PDB ID:
4DPF
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MMDB ID:
101205
PDB Deposition Date:
2012/2/13
Updated in MMDB:
2012/07
Experimental Method:
x-ray diffraction
Resolution:
1.8 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4DPF: monomeric; determined by author and by software (PISA)
Molecular Components in 4DPF
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[(4s,8e,11s)-4-[(1r)-1-Hydroxy-2-{[3-(Propan-2-Yl)benzyl]amino}ethyl]-2,13-Dioxo-11-Phenyl-6-Oxa-3,12-Diazabicyclo[12.3.1]octadeca-1(18),8,14,16-Tetraen-16-Yl]-N-Methylmethanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303