4E73: Crystal structure of JNK1beta-JIP in complex with an azaquinolone inhbitor

PDB ID: 4E73Download
MMDB ID: 110489
PDB Deposition Date: 2012/3/16
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Similar Structures:
Biological Unit for 4E73: dimeric; determined by author and by software (PISA)
Molecular Components in 4E73
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 8
(Gene symbol: MAPK8)
Molecule annotation
1
C-jun-amino-terminal Kinase-interacting Protein 1
(Gene symbol: MAPK8IP1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
methyl 3-(4-{[(1R,2S,3S,5S,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylatemethyl 3-(4-{[(1R,2S,3S,5S,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303