3MO5: Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72

PDB ID: 3MO5Download
MMDB ID: 83082
PDB Deposition Date: 2010/4/22
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.14  Å
Source Organism:
Similar Structures:
Biological Unit for 3MO5: monomeric; determined by author
Molecular Components in 3MO5
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 5
(Gene symbol: EHMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
ZINC IONZINC ION
2
1
7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303