4FOD: Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36

PDB ID: 4FODDownload
MMDB ID: 101265
PDB Deposition Date: 2012/6/20
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4FOD: monomeric; determined by author and by software (PISA)
Molecular Components in 4FOD
Label Count Molecule
Protein (1 molecule)
1
ALK Tyrosine Kinase Receptor
(Gene symbol: ALK)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-fluoro-N-{(2E)-6-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-1-[cis-4-(propan-2-ylcarbamoyl)cyclohexyl]-1,3-dihydro-2H-benzimidazol-2-ylidene}benzamide4-fluoro-N-{(2E)-6-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-1-[cis-4-(propan-2-ylcarbamoyl)cyclohexyl]-1,3-dihydro-2H-benzimidazol-2-ylidene}benzamide
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303