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4E90:
Human phosphodiesterase 9 in complex with inhibitors
PDB ID:
4E90
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MMDB ID:
107936
PDB Deposition Date:
2012/3/20
Updated in MMDB:
2024/03
Experimental Method:
x-ray diffraction
Resolution:
2.5 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4E90: monomeric; determined by author
Molecular Components in 4E90
Label
Count
Molecule
Protein (1 molecule)
A
1
High Affinity Cgmp-specific 3',5'-cyclic Phosphodiesterase 9A
(Gene symbol:
PDE9A
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC ION
2
1
MAGNESIUM ION
3
1
6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303