4FM7: Crystal Structure Of Bace With Compound 14g

PDB ID: 4FM7Download
MMDB ID: 103561
PDB Deposition Date: 2012/6/15
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 1.56  Å
Source Organism:
Similar Structures:
Biological Unit for 4FM7: monomeric; determined by author and by software (PISA)
Molecular Components in 4FM7
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-{[(5r,7s)-1-(3-Fluorophenyl)-3,7-Dimethyl-2,2-Dioxido-2-Thia-1,3,8-Triazaspiro[4.5]dec-8-Yl]methyl}-2-(Propan-2-Yloxy)phenol4-{[(5r,7s)-1-(3-Fluorophenyl)-3,7-Dimethyl-2,2-Dioxido-2-Thia-1,3,8-Triazaspiro[4.5]dec-8-Yl]methyl}-2-(Propan-2-Yloxy)phenol
2
2
Zinc IonZinc Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303