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4FM8:
Crystal Structure Of Bace With Compound 12a
PDB ID:
4FM8
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MMDB ID:
103562
PDB Deposition Date:
2012/6/15
Updated in MMDB:
2012/10
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4FM8: monomeric; determined by author and by software (PISA)
Molecular Components in 4FM8
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(5r,7s)-1-(3-Fluorophenyl)-3,7-Dimethyl-8-[3-(Propan-2-Yloxy)benzyl]-2-Thia-1,3,8-Triazaspiro[4.5]decane 2,2-Dioxide
2
1
Zinc Ion
3
1
1,2-Ethanediol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303