4HWT: Crystal Structure Of Human Threonyl-trna Synthetase Bound To A Novel Inhibitor

PDB ID: 4HWTDownload
MMDB ID: 113545
PDB Deposition Date: 2012/11/8
Updated in MMDB: 2013/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4HWT: dimeric; determined by author and by software (PISA)
Molecular Components in 4HWT
Label Count Molecule
Proteins (2 molecules)
2
Threonine--trna Ligase, Cytoplasmic
(Gene symbol: TARS1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
Zinc IonZinc Ion
2
2
N-{[3-(2h-Indazol-5-Yl)phenyl]sulfonyl}-L-ThreoninamideN-{[3-(2h-Indazol-5-Yl)phenyl]sulfonyl}-L-Threoninamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303