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4HVB:
Catalytic unit of PI3Kg in complex with PI3K/mTOR dual inhibitor PF-04979064
PDB ID:
4HVB
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MMDB ID:
115274
PDB Deposition Date:
2012/11/5
Updated in MMDB:
2013/11
Experimental Method:
x-ray diffraction
Resolution:
2.35 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4HVB: monomeric; determined by author and by software (PISA)
Molecular Components in 4HVB
Label
Count
Molecule
Protein (1 molecule)
A
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol:
PIK3CG
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-{1-[(2S)-2-hydroxypropanoyl]piperidin-4-yl}-3-methyl-8-(6-methylpyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c][1,5]naphthyridin-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303