4HT2: Crystal structure of human carbonic anhydrase isozyme XII with the inhibitor

PDB ID: 4HT2Download
MMDB ID: 109037
PDB Deposition Date: 2012/10/31
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 4HT2: monomeric; determined by author and by software (PISA)
Molecular Components in 4HT2
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 12
(Gene symbol: CA12)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
ZINC IONZINC ION
2
1
4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303