4BCO: Structure Of Cdk2 In Complex With Cyclin A And A 2-amino-4- Heteroaryl-pyrimidine Inhibitor

PDB ID: 4BCODownload
MMDB ID: 106516
PDB Deposition Date: 2012/10/2
Updated in MMDB: 2013/02
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Bos taurus▼
Similar Structures:
Biological Unit for 4BCO: dimeric; determined by software (PISA)
Molecular Components in 4BCO
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
Molecule annotation
1
Cyclin-a2
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-[[3-(4-Ethanoyl-1,4-Diazepan-1-Yl)phenyl]amino]-4-[4-Methyl-2-(Methylamino)-1,3-Thiazol-5-Yl]pyrimidine-5-Carbonitrile2-[[3-(4-Ethanoyl-1,4-Diazepan-1-Yl)phenyl]amino]-4-[4-Methyl-2-(Methylamino)-1,3-Thiazol-5-Yl]pyrimidine-5-Carbonitrile
2
2
MonothioglycerolMonothioglycerol
3
2
Sulfate IonSulfate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303