4JQ8: Crystal structure of EGFR kinase domain in complex with compound 4b

PDB ID: 4JQ8Download
MMDB ID: 111098
PDB Deposition Date: 2013/3/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.83  Å
Source Organism:
Similar Structures:
Biological Unit for 4JQ8: dimeric; determined by author and by software (PISA)
Molecular Components in 4JQ8
Label Count Molecule
Proteins (2 molecules)
2
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]-N~3~,N~3~-dimethyl-beta-alaninamideN-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]-N~3~,N~3~-dimethyl-beta-alaninamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303