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4HYH:
X-RAY Crystal structure of compound 39 bound to human chk1 kinase domain
PDB ID:
4HYH
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MMDB ID:
108180
PDB Deposition Date:
2012/11/13
Updated in MMDB:
2013/05
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4HYH: monomeric; determined by author and by software (PISA)
Molecular Components in 4HYH
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase Chk1
(Gene symbol:
CHEK1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303