4HYI: X-RAY Crystal structure of compound 40 bound to human chk1 kinase domain

PDB ID: 4HYIDownload
MMDB ID: 108181
PDB Deposition Date: 2012/11/13
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.399  Å
Source Organism:
Similar Structures:
Biological Unit for 4HYI: monomeric; determined by author and by software (PISA)
Molecular Components in 4HYI
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Chk1
(Gene symbol: CHEK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
GLYCEROLGLYCEROL
2
1
2-(1H-indazol-1-yl)-N-[2-(piperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide2-(1H-indazol-1-yl)-N-[2-(piperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303