4IKS: Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(6-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine

PDB ID: 4IKSDownload
MMDB ID: 115835
PDB Deposition Date: 2012/12/28
Updated in MMDB: 2013/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4IKS: monomeric; determined by author and by software (PISA)
Molecular Components in 4IKS
Label Count Molecule
Protein (1 molecule)
1
Methionine Aminopeptidase 1
(Gene symbol: METAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
N-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-N'-[6-(trifluoromethyl)pyridin-2-yl]ethane-1,2-diamineN-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-N'-[6-(trifluoromethyl)pyridin-2-yl]ethane-1,2-diamine
2
3
COBALT (II) IONCOBALT (II) ION
3
1
POTASSIUM IONPOTASSIUM ION
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303