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4GFO:
TYK2 kinase (JH1 domain) with 2,6-DICHLORO-N-(2-OXO-2,5-DIHYDROPYRIDIN-4-YL)BENZAMIDE
PDB ID:
4GFO
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MMDB ID:
111048
PDB Deposition Date:
2012/8/3
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4GFO: monomeric; determined by author and by software (PISA)
Molecular Components in 4GFO
Label
Count
Molecule
Protein (1 molecule)
A
1
Non-receptor Tyrosine-protein Kinase Tyk2
(Gene symbol:
TYK2
)
Chemicals and Non-standard biopolymers (6 molecules)
1
2
SULFATE ION
2
2
1,2-ETHANEDIOL
3
1
GLYCEROL
4
1
2,6-dichloro-N-(2-oxo-2,5-dihydropyridin-4-yl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303