3TUH: Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib

PDB ID: 3TUHDownload
MMDB ID: 103000
PDB Deposition Date: 2011/9/16
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3TUH: monomeric; determined by author and by software (PISA)
Molecular Components in 3TUH
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303