4L5B: Human dCK C4S-S74E mutant in complex with UDP and the DI-43 inhibitor

PDB ID: 4L5BDownload
MMDB ID: 113601
PDB Deposition Date: 2013/6/10
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 1.94  Å
Source Organism:
Similar Structures:
Biological Unit for 4L5B: dimeric; determined by author and by software (PISA)
Molecular Components in 4L5B
Label Count Molecule
Proteins (2 molecules)
2
Deoxycytidine Kinase
(Gene symbol: DCK)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
1-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]-2-methylpropan-2-ol1-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]-2-methylpropan-2-ol
2
2
URIDINE-5'-DIPHOSPHATEURIDINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303