4K8A: Fragment-based discovery of Focal Adhesion Kinase Inhibitors

PDB ID: 4K8ADownload
MMDB ID: 113414
PDB Deposition Date: 2013/4/18
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.91  Å
Source Organism:
Similar Structures:
Biological Unit for 4K8A: dimeric; determined by author
Molecular Components in 4K8A
Label Count Molecule
Proteins (2 molecules)
2
Focal Adhesion Kinase 1
(Gene symbol: PTK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-bromo-5-(2H-tetrazol-5-yl)pyridine3-bromo-5-(2H-tetrazol-5-yl)pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303