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4JYV:
Structure Of Factor Viia In Complex With The Inhibitor (2r)-2-[3- Ethoxy-4-(propan-2-yloxy)phenyl]-2-(isoquinolin-6-ylamino)-n-[(3- Sulfamoylphenyl)sulfonyl]ethanamide
PDB ID:
4JYV
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MMDB ID:
112073
PDB Deposition Date:
2013/4/1
Updated in MMDB:
2013/09
Experimental Method:
x-ray diffraction
Resolution:
2.19 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4JYV: dimeric; determined by author and by software (PISA)
Molecular Components in 4JYV
Label
Count
Molecule
Proteins (2 molecules)
H
1
Factor VII Light Chain
(Gene symbol:
F7
)
L
1
Factor VII Heavy Chain
(Gene symbol:
F7
)
Chemicals and Non-standard biopolymers (10 molecules)
1
1
(2r)-2-[3-Ethoxy-4-(Propan-2-Yloxy)phenyl]-2-(Isoquinolin-6-Ylamino)-N-[(3-Sulfamoylphenyl)sulfonyl]ethanamide
2
1
Calcium Ion
3
4
Sulfate Ion
4
4
Glycerol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303