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3AMA:
Protein kinase A sixfold mutant model of Aurora B with inhibitor JNJ-7706621
PDB ID:
3AMA
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MMDB ID:
237641
PDB Deposition Date:
2010/8/18
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
1.75 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3AMA: dimeric; determined by author and by software (PISA)
Molecular Components in 3AMA
Label
Count
Molecule
Proteins (2 molecules)
A
1
Camp-dependent Protein Kinase Catalytic Subunit Alpha
(Gene symbol:
PRKACA
)
B
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol:
PKIA
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303