4FKO: Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor

PDB ID: 4FKODownload
MMDB ID: 109845
PDB Deposition Date: 2012/6/13
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 4FKO: monomeric; determined by author and by software (PISA)
Molecular Components in 4FKO
Label Count Molecule
Protein (1 molecule)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2-chloro-N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethylbenzene-1,4-diamine2-chloro-N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethylbenzene-1,4-diamine
2
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303