3ZTX: Aurora Kinase Selective Inhibitors Identified Using A Taxol- Induced Checkpoint Sensitivity Screen

PDB ID: 3ZTXDownload
MMDB ID: 96961
PDB Deposition Date: 2011/7/12
Updated in MMDB: 2012/02
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZTX: dimeric; determined by author and by software (PISA)
Molecular Components in 3ZTX
Label Count Molecule
Proteins (2 molecules)
1
Serine/threonine-protein Kinase 12-a
(Gene symbol: aurkb.L)
Molecule annotation
1
Inner Centromere Protein a
(Gene symbol: incenp.L)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5h-benzo[e]pyrimido [5,4-b][1,4]diazepin-6(11h)-one2-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5h-benzo[e]pyrimido [5,4-b][1,4]diazepin-6(11h)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303