4FW6: Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOBUTAN-2-YL]-4-(PHENYLETHYNYL)BENZAMIDE inhibitor

PDB ID: 4FW6Download
MMDB ID: 110088
PDB Deposition Date: 2012/6/29
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 4FW6: monomeric; determined by author and by software (PISA)
Molecular Components in 4FW6
Label Count Molecule
Protein (1 molecule)
1
Udp-3-o-[3-hydroxymyristoyl] N-acetylglucosamine Deacetylase
(Gene symbol: lpxC)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
ZINC IONZINC ION
2
1
N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamideN-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide
3
2
GLYCEROLGLYCEROL
4
3
ACETATE IONACETATE ION
5
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303