4EFS: Human MMP12 in complex with L-glutamate motif inhibitor

PDB ID: 4EFSDownload
MMDB ID: 100722
PDB Deposition Date: 2012/3/30
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 4EFS: monomeric; determined by author and by software (PISA)
Molecular Components in 4EFS
Label Count Molecule
Protein (1 molecule)
1
Macrophage Metalloelastase
(Gene symbol: MMP12)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
ZINC IONZINC ION
2
3
CALCIUM IONCALCIUM ION
3
1
N~2~-[4-(4-phenylthiophen-2-yl)benzoyl]-L-alpha-glutamineN~2~-[4-(4-phenylthiophen-2-yl)benzoyl]-L-alpha-glutamine
4
1
GLYCEROLGLYCEROL
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
R-1,2-PROPANEDIOLR-1,2-PROPANEDIOL
7
3
S-1,2-PROPANEDIOLS-1,2-PROPANEDIOL
8
1
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303