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MMDB Description
24709a Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR
26789Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
26790Structural Basis for 3-deoxy-cdca Binding and Activation of FXR
63159Structure of Human FXR in Complex With Mfa-1 and CO- Activator Peptide
66041FXR With Src1 and Gw4064
66042FXR With Src1 and Gsk8062
78874Discovery of Xl335, a Highly Potent, Selective and Orally- Active Agonist of the Farnesoid X Receptor (Fxr)
70843Identification of an N-oxide Pyridine Gw4064 Analogue as a Potent FXR Agonist
75146Isoxazole Ligand Bound to Farnesoid X Receptor (Fxr)
75477FXR With Src1 and Gsk826
75478FXR With Src1 and Gsk088
80507Complex Structure of FXR Ligand-binding Domain With a Tetrahydroazepinoindole Compound
87622Crystal Structure of Human FXR in Complex With 2-(4-chlorophenyl)-1- [(1s)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1h-benzimidazole- 6-carboxylic Acid
87623Crystal Structure of Human FXR in Complex With (2s)-2-[2-(4- Chlorophenyl)-1h-benzimidazol-1-yl]-n,2-dicyclohexylethanamide
88071Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3-methylbenzoic Acid
88072Crystal Structure of Human FXR in Complex With (2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2-cyclohexyl-n-(2- Methylphenyl)ethanamide
88073Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3-fluorobenzoic Acid
88077Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)benzoic Acid
88078Crystal Structure of Human FXR in Complex With 4-({(2s)-2-[2-(4- Chlorophenyl)-5,6-difluoro-1h-benzimidazol-1-yl]-2- Cyclohexylacetyl}amino)-3,5-difluorobenzoic Acid